Biocomputing Publications

Title Authors Journal Year of Publication DOI Pubmed ID
Title
Human and mouse essentiality screens as a resource for disease gene discovery
Authors
P. Cacheiro, V. Munoz-Fuentes, S.A. Murray, M.E. Dickinson, M. Bucan, L.M.J. Nutter, K.A. Peterson, H. Haselimashhadi, A.M. Flenniken, H. Morgan, H. Westerberg, T. Konopka, C.W. Hsu, A. Christiansen, D.G. Lanza, A.L. Beaudet, J.D. Heaney, H. Fuchs, V. Gailus-Durner, T. Sorg, J. Prochazka, V. Novosadova, C.J. Lelliott, H. Wardle-Jones, S. Wells, L. Teboul, H. Cater, M. Stewart, T. Hough, W. Wurst, R. Sedlacek, D.J. Adams, J.R. Seavitt, G. Tocchini-Valentini, F. Mammano, R.E. Braun, C. McKerlie, Y. Herault, M.H. de Angelis, A.M. Mallon, K.C.K. Lloyd, S.D.M. Brown, H. Parkinson, T.F. Meehan, D. Smedley
Journal
Nat Commun
Year
2020
DOI
10.1038/s41467-020-14284-2
Title
The Deep Genome Project
Authors
K.C.K. Lloyd, D.J. Adams, G. Baynam, A.L. Beaudet, F. Bosch, K.M. Boycott, R.E. Braun, M. Caulfield, R. Cohn, M.E. Dickinson, M.S. Dobbie, A.M. Flenniken, P. Flicek, S. Galande, X. Gao, A. Grobler, J.D. Heaney, Y. Herault, M.H. de Angelis, J.R. Lupski, S. Lyonnet, A.M. Mallon, F. Mammano, C.A. MacRae, R. McInnes, C. McKerlie, T.F. Meehan, S.A. Murray, L.M.J. Nutter, Y. Obata, H. Parkinson, M.S. Pepper, R. Sedlacek, J.K. Seong, T. Shiroishi, D. Smedley, G. Tocchini-Valentini, D. Valle, C.L. Wang, S. Wells, J. White, W. Wurst, Y. Xu, S.D.M. Brown
Journal
Genome Biol
Year
2020
DOI
10.1186/s13059-020-1931-9
Title
High-throughput discovery of genetic determinants of circadian misalignment
Authors
T. Zhang, P. Xie, Y. Dong, Z. Liu, F. Zhou, D. Pan, Z. Huang, Q. Zhai, Y. Gu, Q. Wu, N. Tanaka, Y. Obata, A. Bradley, C.J. Lelliott, L.M.J. Nutter, C. McKerlie, A.M. Flenniken, M.F. Champy, T. Sorg, Y. Herault, M.H. Angelis, V.G. Durner, A.M. Mallon, S.D.M. Brown, T. Meehan, H.E. Parkinson, D. Smedley, K.C.K. Lloyd, J. Yan, X. Gao, J.K. Seong, C.L. Wang, R. Sedlacek, Y. Liu, J. Rozman, L. Yang, Y. Xu
Journal
PLoS Genet
Year
2020
DOI
10.1371/journal.pgen.1008577
Title
Mice With a Brd4 Mutation Represent a New Model of Nephrocalcinosis
Authors
C.M. Gorvin, N.Y. Loh, M.J. Stechman, S. Falcone, F.M. Hannan, B.N. Ahmad, S.E. Piret, A.A. Reed, J. Jeyabalan, P. Leo, M. Marshall, S. Sethi, P. Bass, I. Roberts, J. Sanderson, S. Wells, T.A. Hough, L. Bentley, P.T. Christie, M.M. Simon, A.M. Mallon, H. Schulz, R.D. Cox, M.A. Brown, N. Huebner, S.D. Brown, R.V. Thakker
Journal
J Bone Miner Res
Year
2019
DOI
10.1002/jbmr.3695
Title
An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice
Authors
C.M. Gorvin, B.N. Ahmad, M.J. Stechman, N.Y. Loh, T.A. Hough, P. Leo, M. Marshall, S. Sethi, L. Bentley, S.E. Piret, A. Reed, J. Jeyabalan, P.T. Christie, S. Wells, M.M. Simon, A.M. Mallon, H. Schulz, N. Huebner, M.A. Brown, R.D. Cox, S.D. Brown, R.V. Thakker
Journal
J Bone Miner Res
Year
2019
DOI
10.1002/jbmr.3624
Title
Genomic Mutation Identification in Mice Using Illumina Sequencing and Linux-Based Computational Methods
Authors
J.A. Williams, G. Powell, A.M. Mallon, M.M. Simon
Journal
Curr Protoc Mouse Biol
Year
2019
DOI
10.1002/cpmo.64
Title
Soft Windowing Application to Improve Analysis of High-throughput Phenotyping Data
Authors
H. Haselimashhadi, J.C. Mason, V. Munoz-Fuentes, F. Lopez-Gomez, K. Babalola, E.F. Acar, V. Kumar, J. White, A.M. Flenniken, R. King, E. Straiton, J.R. Seavitt, A. Garza, A.E. Christianson, C.W. Hsu, C.L. Reynolds, D.G. Lanza, I. Lorenzo, J.R. Green, J.J. Gallegos, R. Bohat, R.C. Samaco, S. Veeraragavan, J.K. Kim, G. Miller, H. Fuchs, L. Garrett, L. Becker, Y.K. Kang, D. Clary, S.Y. Cho, M. Tamura, N. Tanaka, K.D. Soo, A. Bezginov, G.B. About, M.F. Champy, L. Vasseur, S. Leblanc, H. Meziane, M. Selloum, P.T. Reilly, N. Spielmann, H. Maier, V. Gailus-Durner, T. Sorg, M. Hiroshi, O. Yuichi, J.D. Heaney, M.E. Dickinson, W. Wolfgang, G.P. Tocchini-Valentini, K.C.K. Lloyd, C. McKerlie, J.K. Seong, H. Yann, M.H. de Angelis, S.D.M. Brown, D. Smedley, P. Flicek, A.M. Mallon, H. Parkinson, T.F. Meehan
Journal
Bioinformatics
Year
2019
DOI
10.1093/bioinformatics/btz744
Title
Protection Against XY Gonadal Sex Reversal by a Variant Region on Mouse Chromosome 13
Authors
C. Livermore, M. Simon, R. Reeves, I. Stevant, S. Nef, M. Pope, A.M. Mallon, S. Wells, N. Warr, A. Greenfield
Journal
Genetics
Year
2019
DOI
10.1534/genetics.119.302786
Title
Reproducibility and replicability of rodent phenotyping in preclinical studies
Authors
N. Kafkafi, J. Agassi, E.J. Chesler, J.C. Crabbe, W.E. Crusio, D. Eilam, R. Gerlai, I. Golani, A. Gomez-Marin, R. Heller, F. Iraqi, I. Jaljuli, N.A. Karp, H. Morgan, G. Nicholson, D.W. Pfaff, S.H. Richter, P.B. Stark, O. Stiedl, V. Stodden, L.M. Tarantino, V. Tucci, W. Valdar, R.W. Williams, H. Wurbel, Y. Benjamini
Journal
Neurosci Biobehav Rev
Year
2018
DOI
10.1016/j.neubiorev.2018.01.003
Pubmed ID
PMC6071910
Title
Identification of genetic elements in metabolism by high-throughput mouse phenotyping
Authors
J. Rozman, B. Rathkolb, M.A. Oestereicher, C. Schutt, A.C. Ravindranath, S. Leuchtenberger, S. Sharma, M. Kistler, M. Willershauser, R. Brommage, T.F. Meehan, J. Mason, H. Haselimashhadi, T. Hough, A.M. Mallon, S. Wells, L. Santos, C.J. Lelliott, J.K. White, T. Sorg, M.F. Champy, L.R. Bower, C.L. Reynolds, A.M. Flenniken, S.A. Murray, L.M.J. Nutter, K.L. Svenson, D. West, G.P. Tocchini-Valentini, A.L. Beaudet, F. Bosch, R.B. Braun, M.S. Dobbie, X. Gao, Y. Herault, A. Moshiri, B.A. Moore, K.C.Kent Lloyd, C. McKerlie, H. Masuya, N. Tanaka, P. Flicek, H.E. Parkinson, R. Sedlacek, J.K. Seong, C.L. Wang, M. Moore, S.D. Brown, M.H. Tschop, W. Wurst, M. Klingenspor, E. Wolf, J. Beckers, F. Machicao, A. Peter, H. Staiger, H.U. Haring, H. Grallert, M. Campillos, H. Maier, H. Fuchs, V. Gailus-Durner, T. Werner, H. de Angelis
Journal
Nat Commun
Year
2018
DOI
10.1038/s41467-017-01995-2
Pubmed ID
PMC5773596
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