Disease Model Discovery Publications

Title Authors Journal Year of Publication DOI Pubmed ID
Title
A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging
Authors
M. Curley, L. Milne, S. Smith, A. Jorgensen, H. Frederiksen, P. Hadoke, P. Potter, L.B. Smith
Journal
Faseb j
Year
2019
DOI
10.1096/fj.201800612R
Pubmed ID
PMC6355079
Title
The dark genome and pleiotropy: challenges for precision medicine
Authors
S.D.M. Brown, H.V. Lad
Journal
Mamm Genome
Year
2019
DOI
10.1007/s00335-019-09813-4
Pubmed ID
PMC6355079
Title
Modification of an aggressive model of Alport Syndrome reveals early differences in disease pathogenesis due to genetic background
Authors
S. Falcone, L. Wisby, T. Nicol, A. Blease, B. Starbuck, A. Parker, J. Sanderson, S.D.M. Brown, C.L. Scudamore, C.D. Pusey, F.W.K. Tam, P.K. Potter
Journal
Sci Rep
Year
2019
DOI
10.1038/s41598-019-56837-6
Pubmed ID
PMC6355079
Title
Studying Osteoarthritis Pathogenesis in Mice
Authors
A. Blease, D.Neves Borges, M. Curtinha, B. Javaheri, I.S. von Loga, I. Parisi, J. Zarebska, A. Pitsillides, T.L. Vincent, P.K. Potter
Journal
Curr Protoc Mouse Biol
Year
2018
DOI
10.1002/cpmo.50
Pubmed ID
PMC6355079
Title
Mouse Idh3a mutations cause retinal degeneration and reduced mitochondrial function
Authors
A.S. Findlay, R.N. Carter, B. Starbuck, L. McKie, K. Novakova, P.S. Budd, M.A. Keighren, J.A. Marsh, S.H. Cross, M.M. Simon, P.K. Potter, N.M. Morton, I.J. Jackson
Journal
Dis Model Mech
Year
2018
DOI
10.1242/dmm.036426
Pubmed ID
PMC6307916
Title
Does age matter? The impact of rodent age on study outcomes
Authors
S.J. Jackson, N. Andrews, D. Ball, I. Bellantuono, J. Gray, L. Hachoumi, A. HOLMES, J. Latcham, A. Petrie, P. Potter, A. Rice, A. Ritchie, M. Stewart, C. Strepka, M. Yeoman, K. Chapman
Journal
Lab Anim
Year
2017
DOI
10.1177/0023677216653984
Pubmed ID
PMC5367550
Title
With mouse age comes wisdom: A review and suggestions of relevant mouse models for age-related conditions
Authors
S. Drechsler, M.A. Lynch, S. Novella, H. Gonzalez-Navarro, S. Hecimovic, E. Barini, V. Tucci, R.E. Castro, R.E. Vandenbroucke, M. Osuchowski, P.K. Potter
Journal
Mech Ageing Dev
Year
2016
DOI
10.1016/j.mad.2016.07.005
Pubmed ID
PMC5367550
Title
Mouse models of ageing and their relevance to disease
Authors
S. Koks, S. Dogan, B.G. Tuna, H. Gonzalez-Navarro, P. Potter, R.E. Vandenbroucke
Journal
Mech Ageing Dev
Year
2016
DOI
10.1016/j.mad.2016.10.001
Pubmed ID
PMC5367550
Title
Genome-wide association of multiple complex traits in outbred mice by ultra-low-coverage sequencing
Authors
J. Nicod, R.W. Davies, N. Cai, C. Hassett, L. Goodstadt, C. Cosgrove, B.K. Yee, V. Lionikaite, R.E. McIntyre, C.A. Remme, E.M. Lodder, J.S. Gregory, T. Hough, R. Joynson, H. Phelps, B. Nell, C. Rowe, J. Wood, A. Walling, N. Bopp, A. Bhomra, P. Hernandez-Pliego, J. Callebert, R.M. Aspden, N.P. Talbot, P.A. Robbins, M. Harrison, M. Fray, J.M. Launay, Y.M. Pinto, D.A. Blizard, C.R. Bezzina, D.J. Adams, P. Franken, T. Weaver, S. Wells, S.D. Brown, P.K. Potter, P. Klenerman, A. Lionikas, R. Mott, J. Flint
Journal
Nat Genet
Year
2016
DOI
10.1038/ng.3595
Pubmed ID
PMC4966644
Title
Novel gene function revealed by mouse mutagenesis screens for models of age-related disease
Authors
P.K. Potter, M.R. Bowl, P. Jeyarajan, L. Wisby, A. Blease, M.E. Goldsworthy, M.M. Simon, S. Greenaway, V. Michel, A. Barnard, C. Aguilar, T. Agnew, G. Banks, A. Blake, L. Chessum, J. Dorning, S. Falcone, L. Goosey, S. Harris, A. Haynes, I. Heise, R. Hillier, T. Hough, A. Hoslin, M. Hutchison, R. King, S. Kumar, H.V. Lad, G. Law, R.E. MacLaren, S. Morse, T. Nicol, A. Parker, K. Pickford, S. Sethi, B. Starbuck, F. Stelma, M. Cheeseman, S.H. Cross, R.G. Foster, I.J. Jackson, S.N. Peirson, R.V. Thakker, T. Vincent, C. Scudamore, S. Wells, A. El-Amraoui, C. Petit, A. Acevedo-Arozena, P.M. Nolan, R. Cox, A.M. Mallon, S.D. Brown
Journal
Nat Commun
Year
2016
DOI
10.1038/ncomms12444
Pubmed ID
PMC4992138
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