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Title Authors Journal Year of Publication DOI Pubmed ID
NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice E. Meimaridou; M. Goldsworthy; V. Chortis; E. Fragouli; P.A. Foster; W. Arlt; R. Cox; L.A. Metherell J Endocrinol 2018 10.1530/joe-16-0638
An N-ethyl-N-nitrosourea (ENU)-induced Tyr265Stop mutation of the DNA polymerase accessory subunit gamma 2 (Polg2) is associated with renal calcification in mice C.M. Gorvin; B.N. Ahmad; M.J. Stechman; N.Y. Loh; T.A. Hough; P. Leo; M. Marshall; S. Sethi; L. Bentley; S.E. Piret; A. Reed; J. Jeyabalan; P.T. Christie; S. Wells; M.M. Simon; A.M. Mallon; H. Schulz; N. Huebner; M.A. Brown; R.D. Cox; S.D. Brown; R.V. Thakker J Bone Miner Res 2018 10.1002/jbmr.3624
FTO demethylase activity is essential for normal bone growth and bone mineralization in mice G. Sachse; C. Church; M. Stewart; H. Cater; L. Teboul; R.D. Cox; F.M. Ashcroft Biochim Biophys Acta 2018 10.1016/j.bbadis.2017.11.027

PMC5798602

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition K.S. Small; M. Todorcevic; M. Civelek; J.S.ElSaye Moustafa; X. Wang; M.M. Simon; J. Fernandez-Tajes; A. Mahajan; M. Horikoshi; A. Hugill; C.A. Glastonbury; L. Quaye; M.J. Neville; S. Sethi; M. Yon; C. Pan; N. Che; A. Vinuela; P.C. Tsai; A. Nag; A. Buil; G. Thorleifsson; A. Raghavan; Q. Ding; A.P. Morris; J.T. Bell; U. Thorsteinsdottir; K. Stefansson; M. Laakso; I. Dahlman; P. Arner; A.L. Gloyn; K. Musunuru; A.J. Lusis; R.D. Cox; F. Karpe; M.I. McCarthy Nat Genet 2018 10.1038/s41588-018-0088-x
Mutant mice with calcium-sensing receptor (CaSR) activation have hyperglycemia, that is rectified by calcilytic therapy V.N. Babinsky; F.M. Hannan; R.D. Ramracheya; Q. Zhang; M.A. Nesbit; A. Hugill; L. Bentley; T.A. Hough; E. Joynson; M. Stewart; A. Aggarwal; M. Prinz-Wohlgenannt; C.M. Gorvin; E. Kallay; S. Wells; R.D. Cox; D. Richards; P. Rorsman; R.V. Thakker Endocrinology 2017 10.1210/en.2017-00111
Gα11 mutation in mice causes hypocalcemia rectifiable by calcilytic therapy C.M. Gorvin; F.M. Hannan; S.A. Howles; V.N. Babinsky; S.E. Piret; A. Rogers; A.J. Freidin; M. Stewart; A. Paudyal; T.A. Hough; M.A. Nesbit; S. Wells; T.L. Vincent; S.D. Brown; R.D. Cox; R.V. Thakker JCI Insight 2017 10.1172/jci.insight.91103

PMC5291742

Cinacalcet corrects hypercalcemia in mice with an inactivating Galpha11 mutation S.A. Howles; F.M. Hannan; C.M. Gorvin; S.E. Piret; A. Paudyal; M. Stewart; T.A. Hough; M.A. Nesbit; S. Wells; S.D. Brown; R.D. Cox; R.V. Thakker JCI Insight 2017 10.1172/jci.insight.96540
Mouse Models of Human GWAS Hits for Obesity and Diabetes in the Post Genomic Era: Time for Reevaluation S. Laber; R.D. Cox Front Endocrinol (Lausanne) 2017 10.3389/fendo.2017.00011

PMC5294391

Disruption of the homeodomain transcription factor orthopedia homeobox (Otp) is associated with obesity and anxiety L. Moir; E.G. Bochukova; R. Dumbell; G. Banks; R.S. Bains; P.M. Nolan; C. Scudamore; M. Simon; K.A. Watson; J. Keogh; E. Henning; A. Hendricks; S. O'Rahilly; I. Barroso; U.K.10K. consortium; A.E. Sullivan; D.C. Bersten; M.L. Whitelaw; S. Kirsch; E. Bentley; I.S. Farooqi; R.D. Cox Mol Metabol 2017 http://dx.doi.org/10.1016/j.molmet.2017.08.006
FTO demethylase activity is essential for normal bone growth and bone mineralization in mice G. Sachse; C. Church; M. Stewart; H. Cater; L. Teboul; R.D. Cox; F.M. Ashcroft Biochim Biophys Acta 2017 10.1016/j.bbadis.2017.11.027

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