MRC Harwell Institute has a dedicated quarantine unit for rederiving SPF mice from stocks that are contaminated with infectious microorganisms or for researchers who are simply returning to the UK.
We are able to perform these services on a line-by-line basis or embark on larger projects such as rederiving collections of lines into new facilities or importing strains for scientists moving to UK universities and Institutes.
We are highly experienced in handling the administrative processes (MTAs, licences etc.) that need to be followed before stocks can to be imported from countries across the world. Material can be imported as live mice, unfrozen epididymides, unfrozen embryos or cryopreserved material.
Our technical teams will use the germplasm supplied to rederive the required strains using IVF and embryo transfer techniques, with most standard background strains being available directly from Harwell.
Following rederivation mice are held in dedicated isolators. These are maintained according to strict SOPs. Stocks which have been co-housed in the same isolator are screened following FELASA recommendations before the required strain is released to the client.