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Mutated ES cells can be obtained from a variety of sources.

The cells are imported, amplified, quality controlled and converted into mice following blastocyst injection. Chimera are obtained and mated for transmission of the genetic modification.

Alleles are extensively validated, combining classical methods (i.e. Southern blot) with new technologies (i.e. ddPCR).   

Find mutated alleles by searching the IMPC web portal and the International Gene Trap Consortium.

To request our services, please complete the Mouse model generation Resource Enquiry form.