A DNA construct can be injected into 0.5-day-old fertilised embryos to produce transgenic mice containing the DNA in every cell.
The DNA construct typically consists of a gene of interest that is expressed in a certain range of tissues. The resulting mice are mated and the DNA construct is then transmitted to offspring.
We have experience with employing a broad range of construct types: including plasmids, BAC, PAC.
Please contact us with enquiries on specific genetic background.