Introduction to Genetically Altered Mice

For: Animal Technicians and Early Career Researchers

This course will cover Mendelian gene inheritance as well as aspects of more complex genetics intended to inform breeding strategies and calculations in establishing new genetically altered lines.

After the course, you will be able to:

• Understand Mendelian gene inheritance
• Predict the outcomes of genetic crosses
• Have a working knowledge of the genetic background of mouse strains
• Understand how to maintain the genetic integrity of inbred lines
• Plan breeding schemes
• Perform multiple allele inheritance calculations
• Understand how Genetically Altered lines can be established from modern transgenic technologies