Services

Harwell offers a wide range of scientific services, including:

  • phenotype-driven screens using ENU chemical mutagenesis
  • the generation of both transgenic and knock-out mice, including access to knock-out resources from the international mouse mutagenesis programme
  • mouse clinic services for phenotyping, from comprehensive primary phenotype screens to more sophisticated secondary and tertiary platforms
  • the Harwell mouse archive, supported by comprehensive quarantine and germfree facilities, enabling the import, re-derivation, archiving and dissemination of mouse lines
  • gene-driven screens using ENU mutagenesis, delivering mutant alleles of genes from the Harwell ENU DNA archive
  • microarray facilities, providing microarray analysis of mammalian gene expression
  • proteomics facilities, offering expertise in protein expression, purification and biochemical analysis

Expert teams of scientists and technicians, state of the art equipment, and a proactive approach to the introduction and utilisation of new technological developments underpin all of the services.

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