A high quality service from experimental design to data generation.

MLC Mouse Services

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Mouse Models

Phenotyping Services

Phenotyping by Disease

Mouse Line Services

Welfare and Ethical Review

Mouse Models

Comprehensive genome engineering, genotyping, breeding, and animal care services from design and model production to generation of appropriate experimental cohorts.

Simple Deletions and Point Mutations

Complex Alleles

Breeding and Maintenance

Phenotyping Services

A wide range of tests to characterise mouse models of human disease that we are constantly striving to develop and expand and can tailor to the specific scientific needs of individual projects.

Embryo Phenotyping at the Mary Lyon Centre

Embryo Phenotyping

Expression and Cre Activity Studies at the Mary Lyon Centre

Expression and Cre Activity Studies

In Vivo Phenotyping at the Mary Lyon Centre

In Vivo Phenotyping

Pathology

Clinical Chemistry

Phenotyping by Disease

We have the expertise and equipment to enable us to model a large variety of different human diseases in mice. Here we provide suggestions on the services we offer that might be suitable depending on your disease area of interest.

Developmental Diseases

Metabolic Diseases

Neurological Diseases

Sensory Diseases

Skeletal/Muscular Diseases

Mouse Line Services

We offer a free archiving service making mouse strains available to the community, can rederive pathogen-free mice, and use Cre/Flp methods that reduce the need to maintain delete mice.

Archiving at the Mary Lyon Centre

Archiving and Distribution

Custom Allele Conversion at the Mary Lyon Centre

Custom Allele Conversion

Mary Lyon Centre Mouse Facility

Mouse Strain Rederivation and Repatriation

Welfare and Ethical Review

The health and welfare of our animals is of paramount importance and we are committed to implementing the 3Rs (the refinement, reduction, and replacement of the use of animals in research) as well as to openness about the use of animals in research.

Welfare

Ethical Reviews at the Mary Lyon Centre

Licensing and Ethical Review

Mouse from Mary Lyon Centre

FAQs and Further Information

Other areas of interest

Advance Training

Get the best training in our state of the art training facility built to provide courses in genetics, pathology, transgenics and more!

GEMM

Submit an application to have your free, novel, genetically altered mouse model generated by the Mary Lyon Centre

Bespoke Mouse Services

Have an unusually complex requirement? Want multiple services conducted under one roof? At the MLC we strive to make research life easier. If you have any requests that are not mentioned on our site, please contact us so we can accommodate you the best we can

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