A high quality service from experimental design to data generation.

At the Mary Lyon Centre at MRC Harwell, we are working to improve our understanding of human disease through the study of mouse models and providing mouse genetics services to scientists around the world. These services cover all aspects of preclinical disease modelling in mice, including mouse model generation, a wide array of phenotyping tests, and archiving and distribution services. We adhere to the highest welfare standards and are proactively committed to implementing the 3Rs for the benefit of mouse health and welfare, while also improving the quality of the scientific data generated.

More about the MLC

Enabling mouse genetics research for academia and industry

View all services

Professional, responsive, and able to keep up with ever-changing demand and tight deadlines. When it comes to mouse research, you'll definitely get the 5-star treatment from the Mary Lyon Centre
- Cryopreservation of mouse sperm service

Advance is a purpose built, high-quality, scientific training centre

Advance will build on MRC Harwell’s strong reputation for providing engaging training courses in mouse genetics, genome editing, pathology, and cryopreservation. Dedicated to improving health and plays a leading role in training future research leaders across a range of biomedical, clinical and health disciplines.

View all our courses

Free bespoke mouse models with GEMM

Submit an application to our yearly GEMM programme which allows researchers to apply for a freely generated mouse line by the Mary Lyon Centre. GEMM offers a comprehensive genome engineering service that can meet researchers’ specific requirements.

Apply to get a free mouse model

Catch up on the latest news to come out of the Mary Lyon Centre

View all news posts

15 March 2023

CLAST-Advance partnership

A new partnership for Animal Technologists training The College of Laboratory Animal Science and Technology (CLAST) and Advance at MRC…

1 March 2023

The Mary Lyon Centre and NanoVation Therapeutics (UK) collaborate in a £1.6M Innovate UK Smart Grant project to create a ‘one-shot’ cure for cancer

1 February 2023

Reduced shipments of live mice – a positive change accelerated by the pandemic

17 January 2023

International consortium awarded £8M to enhance the UK’s nucleic acid therapeutic delivery platforms

Think we can help with your next project?