A high quality service from experimental design to data generation.

At the Mary Lyon Centre at MRC Harwell, we are working to improve our understanding of human disease through the study of mouse models and providing mouse genetics services to scientists around the world. These services cover all aspects of preclinical disease modelling in mice, including mouse model generation, a wide array of phenotyping tests, and archiving and distribution services. We adhere to the highest welfare standards and are proactively committed to implementing the 3Rs for the benefit of mouse health and welfare, while also improving the quality of the scientific data generated.

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Enabling mouse genetics research for academia and industry

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Professional, responsive, and able to keep up with ever-changing demand and tight deadlines. When it comes to mouse research, you'll definitely get the 5-star treatment from the Mary Lyon Centre
- Cryopreservation of mouse sperm service

Advance is a purpose built, high-quality, scientific training centre

Advance will build on MRC Harwell’s strong reputation for providing engaging training courses in mouse genetics, genome editing, pathology, and cryopreservation. Dedicated to improving health and plays a leading role in training future research leaders across a range of biomedical, clinical and health disciplines.

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Free bespoke mouse models with GEMM

Submit an application to our yearly GEMM programme which allows researchers to apply for a freely generated mouse line by the Mary Lyon Centre. GEMM offers a comprehensive genome engineering service that can meet researchers’ specific requirements.

Apply to get a free mouse model

Jobs and prospects at the Mary Lyon Centre

Opportunities to grow and develop your skills and career at the Mary Lyon Centre

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Alternatives to Animal Research Scientific Specialist

Closing date: 13th November 2024

Pathology Technician

Closing date: 10th November 2024

Mechanical Technician

Closing date: 24th November 2024

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Work Experience

Our work experience programme is a valuable opportunity for students to find out more about careers in biomedical science, gain an insight into life in…

Catch up on the latest news to come out of the Mary Lyon Centre

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11 October 2024

Training the future generations of mouse geneticists: the 2024 Mouse Models of Human Disease Workshop

How it started In September 2023, our Advance Training Centre ran the first Mouse Models of Human Disease Workshop to…

8 July 2024

Improving laboratory animal genetic reporting

17 June 2024

Dr Sara Wells, MBE!

11 June 2024

Rare Disease Community Event – meeting report

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