Guidelines and Commentaries

We publish guidelines in areas of relevance to our community, such as mouse pathology, high-throughput phenotyping, and screening and validation of genome-edited animals, as well as commentaries on the latest issues of interest.

The Sex Inclusive Research Framework to address sex bias in preclinical research proposals

Karp, N. A., Berdoy, M., Gray, K., Hunt, L., Jennings, M., Kerton, A., Leach, M., Tremoleda, J. L., Gledhill, J., Pearl, E. J., Percie du Sert, N., Phillips, B., Reynolds, P. S., Ryder, K., Stanford, S. C., Wells, S., Whitfield, L.

(2025) , Nat Commun , 16 , 3763

10.1038/s41467-025-58560-5

40263253

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Parent-of-origin of alleles: an essential variable in in vivo experiments

Teboul, L., Stewart, M. E.

(2025) , Lab Anim (NY) , ,

10.1038/s41684-025-01546-z

40175603

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Better understanding of laboratory animal genetics will improve reproducibility

Pavlovic, G., Wells, S., Hérault, Y., Teboul, L.

(2025) , PLoS Biol , 23 , e3003464

10.1371/journal.pbio.3003464

PMC12588450

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Recommendations for measuring and standardizing light for laboratory mammals to improve welfare and reproducibility in animal research

Lucas, R. J., Allen, A. E., Brainard, G. C., Brown, T. M., Dauchy, R. T., Didikoglu, A., Do, M. T. H., Gaskill, B. N., Hattar, S., Hawkins, P., Hut, R. A., McDowell, R. J., Nelson, R. J., Prins, J. B., Schmidt, T. M., Takahashi, J. S., Verma, V., Voikar, V., Wells, S., Peirson, S. N.

(2024) , PLoS Biol , 22 , e3002535

10.1371/journal.pbio.3002535

PMC10931507

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Model matchmaking via the Solve-RD Rare Disease Models & Mechanisms Network (RDMM-Europe)

Ellwanger, K., Brill, J. A., de Boer, E., Efthymiou, S., Elgersma, Y., Icmat, M., Lecoquierre, F., Lobato, A. G., Morleo, M., Ori, M., Schaffer, A. E., Vitobello, A., Wells, S., Yalcin, B., Zhai, R. G., Sturm, M., Zurek, B., Graessner, H., Bermejo-Sánchez, E., Evangelista, T., Hoogerbrugge, N., Nigro, V., Schüle, R., Verloes, A., Brunner, H., Campeau, P. M., Lasko, P., Riess, O.

(2024) , Lab Anim , 53 , 161-165

10.1038/s41684-024-01395-2

PMC11216991

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