NEURODEGEN

TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43';

TDP-43-M323K causes abnormal brain development and progressive cognitive and motor deficits associated with mislocalised and increased levels of TDP-43

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Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations';

Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations

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ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity';

ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity

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A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits';

A novel knockout mouse for the small EDRK-rich factor 2 (Serf2) showing developmental and other deficits

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Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration';

Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration

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Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis';

Mice with endogenous TDP-43 mutations exhibit gain of splicing function and characteristics of amyotrophic lateral sclerosis

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A genetic modifier suggests that endurance exercise exacerbates Huntington’s Disease';

A genetic modifier suggests that endurance exercise exacerbates Huntington’s Disease

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Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in ‘FUSDelta14’ knockin mice';

Humanized mutant FUS drives progressive motor neuron degeneration without aggregation in ‘FUSDelta14’ knockin mice

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Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration';

Deficiency of the zinc finger protein ZFP106 causes motor and sensory neurodegeneration

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