Consortium Papers

Publications detailing the collaborative efforts of the MLC with international consortia involved in the targeted construction and phenotyping of mutant mouse lines, as well as the archiving and distribution of mouse disease models and disease gene discovery. These include the IMPC, EUMODIC and INFRAFRONTIER.

Identification of genes required for eye development by high-throughput screening of mouse knockouts

Moore, B. A., Leonard, B. C., Sebbag, L., Edwards, S. G., Cooper, A., Imai, D. M., Straiton, E., Santos, L., Reilly, C., Griffey, S. M., Bower, L., Clary, D., Mason, J., Roux, M. J., Meziane, H., Herault, Y., McKerlie, C., Flenniken, A. M., Nutter, L. M. J., Berberovic, Z., Owen, C., Newbigging, S., Adissu, H., Eskandarian, M., Hsu, C. W., Kalaga, S., Udensi, U., Asomugha, C., Bohat, R., Gallegos, J. J., Seavitt, J. R., Heaney, J. D., Beaudet, A. L., Dickinson, M. E., Justice, M. J., Philip, V., Kumar, V., Svenson, K. L., Braun, R. E., Wells, S., Cater, H., Stewart, M., Clementson-Mobbs, S., Joynson, R., Gao, X., Suzuki, T., Wakana, S., Smedley, D., Seong, J. K., Tocchini-Valentini, G., Moore, M., Fletcher, C., Karp, N., Ramirez-Solis, R., White, J. K., de Angelis, M. H., Wurst, W., Thomasy, S. M., Flicek, P., Parkinson, H., Brown, S. D. M., Meehan, T. F., Nishina, P. M., Murray, S. A., Krebs, M. P., Mallon, A. M., Lloyd, K. C. K., Murphy, C. J., Moshiri, A.

(2018) , Commun Biol , 1 , 236


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Prevalence of sexual dimorphism in mammalian phenotypic traits

Karp, N. A., Mason, J., Beaudet, A. L., Benjamini, Y., Bower, L., Braun, R. E., Brown, S. D. M., Chesler, E. J., Dickinson, M. E., Flenniken, A. M., Fuchs, H., Angelis, M. H., Gao, X., Guo, S., Greenaway, S., Heller, R., Herault, Y., Justice, M. J., Kurbatova, N., Lelliott, C. J., Lloyd, K. C. K., Mallon, A. M., Mank, J. E., Masuya, H., McKerlie, C., Meehan, T. F., Mott, R. F., Murray, S. A., Parkinson, H., Ramirez-Solis, R., Santos, L., Seavitt, J. R., Smedley, D., Sorg, T., Speak, A. O., Steel, K. P., Svenson, K. L., Wakana, S., West, D., Wells, S., Westerberg, H., Yaacoby, S., White, J. K.

(2017) , Nat Commun , 8 , 15475


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Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

Meehan, T. F., Conte, N., West, D. B., Jacobsen, J. O., Mason, J., Warren, J., Chen, C. K., Tudose, I., Relac, M., Matthews, P., Karp, N., Santos, L., Fiegel, T., Ring, N., Westerberg, H., Greenaway, S., Sneddon, D., Morgan, H., Codner, G. F., Stewart, M. E., Brown, J., Horner, N., Haendel, M., Washington, N., Mungall, C. J., Reynolds, C. L., Gallegos, J., Gailus-Durner, V., Sorg, T., Pavlovic, G., Bower, L. R., Moore, M., Morse, I., Gao, X., Tocchini-Valentini, G. P., Obata, Y., Cho, S. Y., Seong, J. K., Seavitt, J., Beaudet, A. L., Dickinson, M. E., Herault, Y., Wurst, W., de Angelis, M. H., Lloyd, K. C. K., Flenniken, A. M., Nutter, L. M. J., Newbigging, S., McKerlie, C., Justice, M. J., Murray, S. A., Svenson, K. L., Braun, R. E., White, J. K., Bradley, A., Flicek, P., Wells, S., Skarnes, W. C., Adams, D. J., Parkinson, H., Mallon, A. M., Brown, S. D. M., Smedley, D.

(2017) , Nat Genet , 49 , 1231-1238


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A scoring system for the evaluation of the mutated Crb1/rd8-derived retinal lesions in C57BL/6N mice

Concas, D., Cater, H., Wells, S.

(2017) , F1000Res , 6 , 404


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A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

Bowl, M. R., Simon, M. M., Ingham, N. J., Greenaway, S., Santos, L., Cater, H., Taylor, S., Mason, J., Kurbatova, N., Pearson, S., Bower, L. R., Clary, D. A., Meziane, H., Reilly, P., Minowa, O., Kelsey, L., Tocchini-Valentini, G. P., Gao, X., Bradley, A., Skarnes, W. C., Moore, M., Beaudet, A. L., Justice, M. J., Seavitt, J., Dickinson, M. E., Wurst, W., de Angelis, M. H., Herault, Y., Wakana, S., Nutter, L. M. J., Flenniken, A. M., McKerlie, C., Murray, S. A., Svenson, K. L., Braun, R. E., West, D. B., Lloyd, K. C. K., Adams, D. J., White, J., Karp, N., Flicek, P., Smedley, D., Meehan, T. F., Parkinson, H. E., Teboul, L. M., Wells, S., Steel, K. P., Mallon, A. M., Brown, S. D. M.

(2017) , Nat Commun , 8 , 886


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