Consortium Papers

Publications detailing the collaborative efforts of the MLC with international consortia involved in the targeted construction and phenotyping of mutant mouse lines, as well as the archiving and distribution of mouse disease models and disease gene discovery. These include the IMPC, EUMODIC and INFRAFRONTIER.

Disease model discovery from 3,328 gene knockouts by The International Mouse Phenotyping Consortium

Meehan, T. F., Conte, N., West, D. B., Jacobsen, J. O., Mason, J., Warren, J., Chen, C. K., Tudose, I., Relac, M., Matthews, P., Karp, N., Santos, L., Fiegel, T., Ring, N., Westerberg, H., Greenaway, S., Sneddon, D., Morgan, H., Codner, G. F., Stewart, M. E., Brown, J., Horner, N., Haendel, M., Washington, N., Mungall, C. J., Reynolds, C. L., Gallegos, J., Gailus-Durner, V., Sorg, T., Pavlovic, G., Bower, L. R., Moore, M., Morse, I., Gao, X., Tocchini-Valentini, G. P., Obata, Y., Cho, S. Y., Seong, J. K., Seavitt, J., Beaudet, A. L., Dickinson, M. E., Herault, Y., Wurst, W., de Angelis, M. H., Lloyd, K. C. K., Flenniken, A. M., Nutter, L. M. J., Newbigging, S., McKerlie, C., Justice, M. J., Murray, S. A., Svenson, K. L., Braun, R. E., White, J. K., Bradley, A., Flicek, P., Wells, S., Skarnes, W. C., Adams, D. J., Parkinson, H., Mallon, A. M., Brown, S. D. M., Smedley, D.

(2017) , Nat Genet , 49 , 1231-1238

10.1038/ng.3901

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A scoring system for the evaluation of the mutated Crb1/rd8-derived retinal lesions in C57BL/6N mice

Concas, D., Cater, H., Wells, S.

(2017) , F1000Res , 6 , 404

10.12688/f1000research.11252.1

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A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction

Bowl, M. R., Simon, M. M., Ingham, N. J., Greenaway, S., Santos, L., Cater, H., Taylor, S., Mason, J., Kurbatova, N., Pearson, S., Bower, L. R., Clary, D. A., Meziane, H., Reilly, P., Minowa, O., Kelsey, L., Tocchini-Valentini, G. P., Gao, X., Bradley, A., Skarnes, W. C., Moore, M., Beaudet, A. L., Justice, M. J., Seavitt, J., Dickinson, M. E., Wurst, W., de Angelis, M. H., Herault, Y., Wakana, S., Nutter, L. M. J., Flenniken, A. M., McKerlie, C., Murray, S. A., Svenson, K. L., Braun, R. E., West, D. B., Lloyd, K. C. K., Adams, D. J., White, J., Karp, N., Flicek, P., Smedley, D., Meehan, T. F., Parkinson, H. E., Teboul, L. M., Wells, S., Steel, K. P., Mallon, A. M., Brown, S. D. M.

(2017) , Nat Commun , 8 , 886

10.1038/s41467-017-00595-4

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High-throughput discovery of novel developmental phenotypes

Dickinson, M. E., Flenniken, A. M., Ji, X., Teboul, L., Wong, M. D., White, J. K., Meehan, T. F., Weninger, W. J., Westerberg, H., Adissu, H., Baker, C. N., Bower, L., Brown, J. M., Caddle, L. B., Chiani, F., Clary, D., Cleak, J., Daly, M. J., Denegre, J. M., Doe, B., Dolan, M. E., Edie, S. M., Fuchs, H., Gailus-Durner, V., Galli, A., Gambadoro, A., Gallegos, J., Guo, S., Horner, N. R., Hsu, C. W., Johnson, S. J., Kalaga, S., Keith, L. C., Lanoue, L., Lawson, T. N., Lek, M., Mark, M., Marschall, S., Mason, J., McElwee, M. L., Newbigging, S., Nutter, L. M., Peterson, K. A., Ramirez-Solis, R., Rowland, D. J., Ryder, E., Samocha, K. E., Seavitt, J. R., Selloum, M., Szoke-Kovacs, Z., Tamura, M., Trainor, A. G., Tudose, I., Wakana, S., Warren, J., Wendling, O., West, D. B., Wong, L., Yoshiki, A., MacArthur, D. G., Tocchini-Valentini, G. P., Gao, X., Flicek, P., Bradley, A., Skarnes, W. C., Justice, M. J., Parkinson, H. E., Moore, M., Wells, S., Braun, R. E., Svenson, K. L., de Angelis, M. H., Herault, Y., Mohun, T., Mallon, A. M., Henkelman, R. M., Brown, S. D., Adams, D. J., Lloyd, K. C., McKerlie, C., Beaudet, A. L., Bucan, M., Murray, S. A.

(2016) , Nature , 537 , 508-514

10.1038/nature19356

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INFRAFRONTIER–providing mutant mouse resources as research tools for the international scientific community

INFRAFRONTIER Consortium

(2015) , Nucleic Acids Res , 43 , D1171-D1175

10.1093/nar/gku1193

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