Research supported by MLC
The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.
Leukemia Inhibitory Factor-Receptor is Dispensable for Prenatal Testis Development but is Required in Sertoli cells for Normal Spermatogenesis in Mice
Curley, M., Milne, L., Smith, S., Atanassova, N., Rebourcet, D., Darbey, A., Hadoke, P. W. F., Wells, S., Smith, L. B.
High-resolution muCT of a mouse embryo using a compact laser-driven X-ray betatron source
Cole, J. M., Symes, D. R., Lopes, N. C., Wood, J. C., Poder, K., Alatabi, S., Botchway, S. W., Foster, P. S., Gratton, S., Johnson, S., Kamperidis, C., Kononenko, O., De Lazzari, M., Palmer, C. A. J., Rusby, D., Sanderson, J., Sandholzer, M., Sarri, G., Szoke-Kovacs, Z., Teboul, L., Thompson, J. M., Warwick, J. R., Westerberg, H., Hill, M. A., Norris, D. P., Mangles, S. P. D., Najmudin, Z.
Helios is a key transcriptional regulator of outer hair cell maturation
Chessum, L., Matern, M. S., Kelly, M. C., Johnson, S. L., Ogawa, Y., Milon, B., McMurray, M., Driver, E. C., Parker, A., Song, Y., Codner, G., Esapa, C. T., Prescott, J., Trent, G., Wells, S., Dragich, A. K., Frolenkov, G. I., Kelley, M. W., Marcotti, W., Brown, S. D. M., Elkon, R., Bowl, M. R., Hertzano, R.
FTO demethylase activity is essential for normal bone growth and bone mineralization in mice
Sachse, G., Church, C., Stewart, M., Cater, H., Teboul, L., Cox, R. D., Ashcroft, F. M.
Characterisation and use of a functional Gadd45g bacterial artificial chromosome
Warr, N., May, J., Teboul, L., Suzuki, T., Asami, M., Perry, A. C. F., Wells, S., Greenfield, A.