Research supported by MLC

The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.

Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread

Wong, P. P., Demircioglu, F., Ghazaly, E., Alrawashdeh, W., Stratford, M. R., Scudamore, C. L., Cereser, B., Crnogorac-Jurcevic, T., McDonald, S., Elia, G., Hagemann, T., Kocher, H. M., Hodivala-Dilke, K. M.

(2015) , Cancer Cell , 27 , 123-37

10.1016/j.ccell.2014.10.015

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A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity

Joyce, P. I., McGoldrick, P., Saccon, R. A., Weber, W., Fratta, P., West, S. J., Zhu, N., Carter, S., Phatak, V., Stewart, M., Simon, M., Kumar, S., Heise, I., Bros-Facer, V., Dick, J., Corrochano, S., Stanford, M. J., Luong, T. V., Nolan, P. M., Meyer, T., Brandner, S., Bennett, D. L., Ozdinler, P. H., Greensmith, L., Fisher, E. M., Acevedo-Arozena, A.

(2015) , Hum Mol Genet , 24 , 1883-97

10.1093/hmg/ddu605

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