Methods Development

The MLC contributes to the development of new techniques and research methods in areas such as animal husbandry and welfare, phenotyping of mutant lines, and mouse pathology. We are also at the forefront of improvements to technologies such as CRISPR and the latest imaging techniques.

Dual-Stream Spatiotemporal Networks with Feature Sharing for Monitoring Animals in the Home Cage

Nwokedi, E. I., Bains, R. S., Bidaut, L., Ye, X., Wells, S., Brown, J. M.

(2023) , Sensors , 23 , 9532

10.3390/s23239532

PMC10708582

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An Improved Method for Growing Primary Neurons on Electron Microscopy Grids Co-Cultured with Astrocytes

Kumar, I., Paudyal, A., Kádková, A., Stewart, M., Sørensen, J. B., Radecke, J.

(2023) , Int J Mol Sci , 24 ,

10.3390/ijms242015191

PMC10606997

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A method for TAT-Cre recombinase-mediated floxed allele modification in ex vivo tissue slices

Cheong, S. S., Luis, T. C., Stewart, M., Hillier, R., Hind, M., Dean, C. H.

(2023) , Dis Model Mech , 16 , dmm050267

10.1242/dmm.050267

PMC10629676

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Sectioning and Counting of Motor Neurons in the L3 to L6 Region of the Adult Mouse Spinal Cord

Austin, A., Beresford, L., Price, G., Cunningham, T., Kalmar, B., Yon, M.

(2022) , Curr Protoc , 2 , e428

10.1002/cpz1.428

35617451

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Lightsheet Microscopy

Dyer, L., Parker, A., Paphiti, K., Sanderson, J.

(2022) , Curr Protoc , 2 , e448

10.1002/cpz1.448

35838628

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