Methods Development

The MLC contributes to the development of new techniques and research methods in areas such as animal husbandry and welfare, phenotyping of mutant lines, and mouse pathology. We are also at the forefront of improvements to technologies such as CRISPR and the latest imaging techniques.

Multi-Photon Microscopy

Sanderson, J.,

(2023) , Curr Protoc , 3 , e634

10.1002/cpz1.634

36706245

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Sectioning and Counting of Motor Neurons in the L3 to L6 Region of the Adult Mouse Spinal Cord

Austin, A., Beresford, L., Price, G., Cunningham, T., Kalmar, B., Yon, M.

(2022) , Curr Protoc , 2 , e428

10.1002/cpz1.428

35617451

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Lightsheet Microscopy

Dyer, L., Parker, A., Paphiti, K., Sanderson, J.

(2022) , Curr Protoc , 2 , e448

10.1002/cpz1.448

35838628

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A guide to post-mortem examination procedure in mouse models

Rodrigues, A., Beresford, L., Scudamore, C. L., Yon, M.

(2022) , Lab Anim , , 236772221080827

10.1177/00236772221080827

35360986

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Super-Resolution Fluorescence Microscopy Methods for Assessing Mouse Biology

Valli, J., Sanderson, J.

(2021) , Curr Protoc , 1 , e224

10.1002/cpz1.224

34436832

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