Methods Development
The MLC contributes to the development of new techniques and research methods in areas such as animal husbandry and welfare, phenotyping of mutant lines, and mouse pathology. We are also at the forefront of improvements to technologies such as CRISPR and the latest imaging techniques.
The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities
Herbert, E., Stewart, M., Hutchison, M., Flenniken, A. M., Qu, D., Nutter, L. M. J., McKerlie, C., Hobson, L., Kick, B., Lyons, B., Wieg, J. P., Doty, R., Aguilar-Pimentel, J. A., Hrabe de Angelis, M., Dickinson, M., Seavitt, J., White, J. K., Scudamore, C. L., Wells, S.
Targeted Mutations in the Mouse via Embryonic Stem Cells
Gertsenstein, M., Mianne, J., Teboul, L., Nutter, L. M. J.
Phenotyping in Mice Using Continuous Home Cage Monitoring and Ultrasonic Vocalization Recordings
Hobson, L., Bains, R. S., Greenaway, S., Wells, S., Nolan, P. M.
Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density
Swan, A. L., Schütt, C., Rozman, J., Del Mar Muñiz Moreno, M., Brmaier, S., Simon, M., Leuchtenberger, S., Griffiths, M., Brommage, R., Keskivali-Bond, P., Grallert, H., Werner, T., Teperino, R., Becker, L., Miller, G., Moshiri, A., Seavitt, J. R., Cissell, D. D., Meehan, T. F., Acar, E. F., Lelliott, C. J., Flenniken, A. M., Champy, M. F., Sorg, T., Ayadi, A., Braun, R. E., Cater, H., Dickinson, M. E., Flicek, P., Gallegos, J., Ghirardello, E. J., Heaney, J. D., Jacquot, S., Lally, C., Logan, J. G., Teboul, L., Mason, J., Spielmann, N., McKerlie, C., Murray, S. A., Nutter, L. M. J., Odfalk, K. F., Parkinson, H., Prochazka, J., Reynolds, C. L., Selloum, M., Spoutil, F., Svenson, K. L., Vales, T. S., Wells, S. E., White, J. K., Sedlacek, R., Wurst, W., Lloyd, K. C. K., Croucher, P. I., Fuchs, H., Williams, G. R., Bassett, D., Gailus-Durner, V., Herault, Y., Mallon, A. M., Brown, S. D. M., Mayer-Kuckuk, P., Hrabe de Angelis, M.