Research supported by MLC

The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.

Investigating audible and ultrasonic noise in modern animal facilities

Parker, A., Hobson, L., Bains, R., Wells, S., Bowl, M.

(2022) , F1000Res , 11 , 651



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Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen

Wotton, J. M., Peterson, E., Flenniken, A. M., Bains, R. S., Veeraragavan, S., Bower, L. R., Bubier, J. A., Parisien, M., Bezginov, A., Haselimashhadi, H., Mason, J., Moore, M. A., Stewart, M. E., Clary, D. A., Delbarre, D. J., Anderson, L. C., D'Souza, A., Goodwin, L. O., Harrison, M. E., Huang, Z., McKay, M., Qu, D., Santos, L., Srinivasan, S., Urban, R., Vukobradovic, I., Ward, C. S., Willett, A. M., Braun, R. E., Brown, S. D. M., Dickinson, M. E., Heaney, J. D., Kumar, V., Lloyd, K. C. K., Mallon, A. M., McKerlie, C., Murray, S. A., Nutter, L. M. J., Parkinson, H., Seavitt, J. R., Wells, S., Samaco, R. C., Chesler, E. J., Smedley, D., Diatchenko, L., Baumbauer, K. M., Young, E. E., Bonin, R. P., Mandillo, S., White, J. K.

(2022) , Pain , 163 , 1139-1157



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Gadd45g is required for timely Sry expression independently of RSPO1 activity

Warr, N., Siggers, P., May, J., Chalon, N., Pope, M., Wells, S., Chaboissier, M. C., Greenfield, A.

(2022) , Reproduction , 163 , 333-340



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Early embryonic lethality in complex I associated p.L104P Nubpl mutant mice

Cheng, C., Cleak, J., Weiss, L., Cater, H., Stewart, M., Wells, S., Columbres, R. C., Shmara, A., Morato Torres, C. A., Zafar, F., Schüle, B., Neumann, J., Hatchwell, E., Kimonis, V.

(2022) , Orphanet J Rare Dis , 17 , 386



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Biallelic DAW1 variants cause a motile ciliopathy characterized by laterality defects and subtle ciliary beating abnormalities

Leslie, J. S., Hjeij, R., Vivante, A., Bearce, E. A., Dyer, L., Wang, J., Rawlins, L., Kennedy, J., Ubeyratna, N., Fasham, J., Irons, Z. H., Craig, S. B., Koenig, J., George, S., Pode-Shakked, B., Bolkier, Y., Barel, O., Mane, S., Frederiksen, K. K., Wenger, O., Scott, E., Cross, H. E., Lorentzen, E., Norris, D. P., Anikster, Y., Omran, H., Grimes, D. T., Crosby, A. H., Baple, E. L.,

(2022) , Genet Med , ,



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