Research supported by MLC

The MLC supports the work of many research groups across a diverse range of disease areas, including hearing loss, type 2 diabetes, sex determination, neurodegeneration and circadian function, to name a few. Such support can include detailed phenotyping in addition to generation and husbandry of mutant mouse lines.

Shift work-like patterns effect on female and male mouse behavior

Banks, G., Nolan, P.M., Bourbia, N.

(2022) , Neurobiol Sleep Circadian Rhythms , 13 , 100082

10.1016/j.nbscr.2022.100082

PMC9576555

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Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing

Newton, S., Kong, F., Carlton, A. J., Aguilar, C., Parker, A., Codner, G. F., Teboul, L., Wells, S., Brown, S. D. M., Marcotti, W., Bowl, M. R.

(2022) , PLoS Genet , 18 , e1009937

10.1371/journal.pgen.1009937

PMC8830789

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Mendelian gene identification through mouse embryo viability screening

Cacheiro, P., Westerberg, C. H., Mager, J., Dickinson, M. E., Nutter, L. M. J., Muñoz-Fuentes, V., Hsu, C. W., Van den Veyver, I. B., Flenniken, A. M., McKerlie, C., Murray, S. A., Teboul, L., Heaney, J. D., Lloyd, K. C. K., Lanoue, L., Braun, R. E., White, J. K., Creighton, A. K., Laurin, V., Guo, R., Qu, D., Wells, S., Cleak, J., Bunton-Stasyshyn, R., Stewart, M., Harrisson, J., Mason, J., Haseli Mashhadi, H., Parkinson, H., Mallon, A. M., Smedley, D.

(2022) , Genome Med , 14 , 119

10.1186/s13073-022-01118-7

PMC9563108

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Investigating audible and ultrasonic noise in modern animal facilities

Parker, A., Hobson, L., Bains, R., Wells, S., Bowl, M.

(2022) , F1000Res , 11 , 651

10.12688/f1000research.111170.1

PMC9334837

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Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen

Wotton, J. M., Peterson, E., Flenniken, A. M., Bains, R. S., Veeraragavan, S., Bower, L. R., Bubier, J. A., Parisien, M., Bezginov, A., Haselimashhadi, H., Mason, J., Moore, M. A., Stewart, M. E., Clary, D. A., Delbarre, D. J., Anderson, L. C., D'Souza, A., Goodwin, L. O., Harrison, M. E., Huang, Z., McKay, M., Qu, D., Santos, L., Srinivasan, S., Urban, R., Vukobradovic, I., Ward, C. S., Willett, A. M., Braun, R. E., Brown, S. D. M., Dickinson, M. E., Heaney, J. D., Kumar, V., Lloyd, K. C. K., Mallon, A. M., McKerlie, C., Murray, S. A., Nutter, L. M. J., Parkinson, H., Seavitt, J. R., Wells, S., Samaco, R. C., Chesler, E. J., Smedley, D., Diatchenko, L., Baumbauer, K. M., Young, E. E., Bonin, R. P., Mandillo, S., White, J. K.

(2022) , Pain , 163 , 1139-1157

10.1097/j.pain.0000000000002481

PMC9100450

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