Amy Southern

I graduated from Cardiff University with a BSc in Biochemistry in 2018. For my placement year I was working with the Respiratory Medicine Unit at the John Radcliffe Hospital in Oxford looking at the different signals released by asthmatic and healthy lung epithelial cells. I presented this work at the British Thoracic Society conference in 2017.

I am now an MRC-funded DPhil student working in the Deafness Group at MRC Harwell. My project aims to find the genetic cause of chronic otitis media (glue ear) in Down syndrome. Otitis media causes hearing loss, which affects children’s speech development and learning at school. Treating it will hopefully allow children with Down syndrome to integrate better with their peers and become more independent young adults.

I am using mouse models and techniques such as qPCR, western blot and immunohistochemistry to find the genes that cause otitis media when present in 3 copies. I presented a poster of my work at the International Society for Otitis Media 2019 conference and won 1st prize, and I have been awarded additional funding from the MRC to put towards specialist training and the creation of my mouse models.