Researchers investigate the role of enhancers in gene function and disease

Researchers at MRC Harwell and the Vavilov Institute of General Genetics have characterised super-enhancers (SEs) and typical-enhancers (TEs) in the mouse genome to further aid our understanding of their possible role in disease. Published in BMC Genomics, the authors primarily identified both enhancer types contribute to tissue-specific gene expression but have no difference in phenotype effect […]